Chemists compound the medication, natural progesterone, into many dosage forms, including troches. This commonly used form of the medication, the progesterone troche (or lozenge), can also have other hormones incorporated into the troche if needed by patients.

It is widely known that progesterone has many benefits and actions in HRT, including lowering blood pressure, increasing bone density and balancing the effects of estrogen. It also helps with anxiety and improves mood. Prescriptions are required for this medication.